Regulation of growth of LNCaP human prostate tumor cells by growth factors and steroid hormones

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Regulation of growth of LNCaP human prostate tumor cells by growth factors and steroid hormones.

The mitogenic activity of several growth factors on androgen responsive LNCaP human prostate tumor cells was studied. A two-fold stimulation of cell proliferation was observed after a culture period of 6 days in 1 ng EGF/ml, 10 ng TGF-alpha/ml or 20 ng basic FGF/ml. TGF-beta (0.02 ng/ml), which did not affect cell proliferation when added alone to the culture medium, inhibited the EGF- and TGF-...

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Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth

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ژورنال

عنوان ژورنال: The Journal of Steroid Biochemistry and Molecular Biology

سال: 1991

ISSN: 0960-0760

DOI: 10.1016/0960-0760(91)90182-5